In vitro antiplasmodial activity of abietane and totarane diterpenes isolated from harpagophytum procumbens devils. Devils claw harpagophytum procumbens plant profiler. Pedaliaceae by gayle engels, josef brinckmann herbalgram. Harpagophytum procumbens the naturopathic herbalist. The results can also be downloaded as a csv file unicode utf8 encoding see status, confidence level, source for definitions.
Health, general biological sciences science and technology, general analgesics dosage and administration antiinflammatory agents antiinflammatory. Harpagophytum procumbens traditional antiinflammatory herbal. You only have to take one look at the grasping fingers extending from its fruit to understand the name. It has always been aamps intention that the african herbal pharmacopoeia is a living database which. Each monograph contains information required by producers, collectors and traders in medicinal plants and extracts as well as technical data needed by researchers, manufacturers and practitioners. Devils claw harpagophytum procumbens, a plant well adapted to the desert. Herbalgram the journal of the american botanical council issue. List item draft assessment report on harpagophytum procumbens.
Plants profile for harpagophytum procumbens devilsclaw. The potatolike bulbs grows to 600 grams, the caudex grows up to 15 cm diameter and 30 cm height. Harpagophytum procumbens, a member of the pedaliaceae family, is a weedy. One area of its use that has become very popular in recent years is in the treatment of inflammatory disorders of the musculoskeletal system and of low back pain. Addendum to the escop monograph on harpagophytum procumbens. This plant gets its name from the appearance of its fruit, which is covered with hooks meant to attach onto animals in order to spread the seeds. In the latter it grows in the provinces of northwest, western free state and northern cape. Harpagophytum definition of harpagophytum by medical. European union herbal monograph on harpagophytum procumbens dc. Large tuberous roots are the part used medicinally for arthritis, rheumatism, fever. Harpagophytum species root herbal medicines compendium. Harpagophytum procumbens is a medicinal plant containing several compounds with pharmaceutical activity. Devils claw also called devils claw root tuber, devils claw secondary root, kalahari devils claw, grapple plant, harpago, wood spider, grapple vine, xwate and radix harpagophyti, is a plant belonging to pedaliaceae family and is inherent to southern africa.
Topics include, study tips, botanical actions, constituents, pharmacy, monographs, nutrition, carbohydrates, proteins, fats, fiber and much more. Harpagophytum procumbens supplement health benefits. Andor harpagophytum zeyheri decne, radix emeahmpc25232006 table 1. Monograph harpagophytum procumbens devils claw introduction historically, harpagophytum procumbens devils claw has been used as an analgesic, a remedy for fevers and allergies, and as a bitter by san bushmen in africa to stimulate gastric enzymes and digestion. Extracts of the secondary roots of the southern african plant, devils claw harpagophytum procumbens provide a herbal drug with a variety of traditional indications. The botanical name, harpagophytum, means hook plant in greek. Devils claw is indigenous to south and south west africa and has always been used by the people who live there to treat indigestion, as a laxative, for problems associated with the blood, to lower fevers, to relieve pain e. For more than half a century, various preparations from h have been continuously used in europe and have become an established traditional treatment for. Overview of comments on community herbal monograph on. Previously, we established shoot culture and in vitro regenerated plants of h. In the pharma dried aqueous extract of harpagophytum proypt. The monograph included a study on the effect of a 60% ethanolic extract on stimulated cytokine release from human monocytes fiebich et al.
Devils claw is possibly effective for back pain and osteoarthritis. Harpagophytum procumbens commonly called devils claw is a tuber vegetable that is used for combatting lower back pain as well as arthritis both osteoarthritis and rheumatoid arthritis. Harpagophytum procumbensdevils claw is a traditional african herbal drug. Medicinal use of this product has not been approved by the fda. It is commonly used in the management of joint diseases like osteoarthritis, and rheumatoid arthritis. Devils claw is an extract obtained from the root of the african plant harpagophytum procumbens. However, when it is incubated with gastric acid, which generates harpagogenin from harpagoside, it tends to lose this activity in oral dose models. Harpagophytum species root definition the article consists of the dried tuberous secondary roots of harpagophytum procumbens burch. Devils claw, or harpagophytum procumbens, is a herbal medication commonly used in the management of several disorders. Effects of devils claw harpagophytum procumbens on the multidrug transporter abcb1p glycoprotein.
Harpagophytum procumbens is a perennial herb with a succulent taproot. Find out information about harpagophytum procumbens. This is amongst the active constituents of devils claw harpagophytum procumbens, widely used in arthritis to reduce pain and inflammation brien et al 2006, qi et al 2006, grant et al 2007. Plants of the genus owe their common name devils claw to the peculiar appearance of their hooked fruit. It appears to have efficacy at this, and may take a few months to reach maximal efficacy so it would be unlikely something like aspirin, which acts fairly fast. Union herbal monograph on harpagophytum procumbens dc. Browse pictures and read growth cultivation information about devils claw, grapple plant, wood spider, harpago harpagophytum procumbens supplied. Secondary tubers called babies develop on fleshy roots growing from the primary tuber. Final positive opinion adopted date added to the inventory. To explore the characteristics, medicinal uses and prescribing considerations of this herb in more detail, check out the references indicated. A bitter african herb, the root of which contains harpagoside. The resulting monographs are designed for both local users of medicinal plants as well as the international pharmaceutical industry. Following up the recommendation of the conference a monograph was.
Harpagophytum procumbens devils claw has been used as an analgesic, a remedy for fever and allergies. Devils claw harpagophytum procumbens is commonly used as an antiinflammatory herb for the conditions such as osteoarthritis, rheumatoid arthritis and other inflammatory conditions. Harpagophytum procumbens article about harpagophytum. Media in category harpagophytum procumbens the following 10 files are in this category, out of 10 total. Pages in category harpagophytum procumbens this category contains only the following page. American botanical council introduction a weedy, spreading perennial with graygreen, lobed leaves, devils claw harpagophytum procumbens and h. They grow from a primary or mother tuber whose taproot can be up to 2 m deep. A possible natural antiinflammatory agent an experimental study article pdf available in iranian journal of. The fruits, roots and the tubers of this plant are used for medicinal purposes. Harpagophytum procumbens, a member of the pedaliaceae family, is a weedy, perennial plant with creeping stems spreading from a. This is the subject of a draft monograph recently issued by the european drug. Harpagophytum procumbens dc harpagophytum zeyheri decne. New and known iridoid and phenylethanoid glycosides from harpagophytum procumbens and their in vitro inhibition of human leukocyte elastase.
Harpagophytum procumbens, a caudiciform known as devils claw, is native to namibia and south africa. See the devils claw monograph for a further discussion of this topic. Harpagoside from devils claw harpagophytum procumbens has oral antiinflammatory activity fig. Harpagophytum procumbens medicine bibliographies cite. Name of the medicinal product to be specified for the individual finished product.
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